{"id":null,"code":"DRUG0005","name":{"valueFi":"Principles of Drug Discovery and Development","valueEn":"Principles of Drug Discovery and Development","valueSv":"Principles of Drug Discovery and Development"},"credits":8.0,"minCredits":5,"maxCredits":8,"tags":[],"createdAt":1790534785903,"contentList":[{"title":{"valueFi":"Osaamistavoitteet","valueEn":"Learning outcomes","valueSv":""},"content":{"valueFi":"Student learns to describe and understand the purpose of the different phases of the drug discovery and development process and discuss particular aspects of each stage of the process. Student can critically evaluate and select appropriate research methods to elucidate the pharmacological and pharmaceutical properties of drug molecules as well as to assess the toxicological and safety profiles of drug candidates during the various stages of non-clinical and clinical drug development. Furthermore, student understands the differences in drug development processes between \"conventional\" small molecule drugs, biologicals, and advanced therapy drugs, as well as biosimilars and generic drugs, which originate from differences in chemical, biological, and pharmacological properties and regulatory requirements. In addition, students can explain the role of intellectual property rights (IPR) in drug development and how this is reflected in the strategies of drug companies. Student understands the ethical guidelines that regulate the use of laboratory animals in research and clinical investigations. Student improves their skills in communication, scientific presenting, and team work by preparing presentations for Journal Clubs and podcasts as well as networking with external experts.","valueEn":"Student learns to describe and understand the purpose of the different phases of the drug discovery and development process and discuss particular aspects of each stage of the process. Student can critically evaluate and select appropriate research methods to elucidate the pharmacological and pharmaceutical properties of drug molecules as well as to assess the toxicological and safety profiles of drug candidates during the various stages of non-clinical and clinical drug development. Furthermore, student understands the differences in drug development processes between \"conventional\" small molecule drugs, biologicals, and advanced therapy drugs, as well as biosimilars and generic drugs, which originate from differences in chemical, biological, and pharmacological properties and regulatory requirements. In addition, students can explain the role of intellectual property rights (IPR) in drug development and how this is reflected in the strategies of drug companies. Student understands the ethical guidelines that regulate the use of laboratory animals in research and clinical investigations. Student improves their skills in communication, scientific presenting, and team work by preparing presentations for Journal Clubs and podcasts as well as networking with external experts.","valueSv":"Student learns to describe and understand the purpose of the different phases of the drug discovery and development process and discuss particular aspects of each stage of the process. Student can critically evaluate and select appropriate research methods to elucidate the pharmacological and pharmaceutical properties of drug molecules as well as to assess the toxicological and safety profiles of drug candidates during the various stages of non-clinical and clinical drug development. Furthermore, student understands the differences in drug development processes between \"conventional\" small molecule drugs, biologicals, and advanced therapy drugs, as well as biosimilars and generic drugs, which originate from differences in chemical, biological, and pharmacological properties and regulatory requirements. In addition, students can explain the role of intellectual property rights (IPR) in drug development and how this is reflected in the strategies of drug companies. Student understands the ethical guidelines that regulate the use of laboratory animals in research and clinical investigations. Student improves their skills in communication, scientific presenting, and team work by preparing presentations for Journal Clubs and podcasts as well as networking with external experts."}},{"title":{"valueFi":"Sisältö","valueEn":"Content","valueSv":""},"content":{"valueFi":"This course consists of topics divided into the following areas: a) General aspects of drug discovery and development processes, b) Biologicals and advanced therapies, c) Drug discovery technologies, and d) Drug delivery technologies. External experts from biotechs and industry present their commercial drug discovery and development projects in Meet the Expert lectures.\r\nLectures will be completed with Journal Clubs on different topics of drug development. Students also prepare podcasts on interesting topics, like hot topics in science, historical cases, challenges in drug discovery and development, ethical considerations, business-related topics etc.","valueEn":"This course consists of topics divided into the following areas: a) General aspects of drug discovery and development processes, b) Biologicals and advanced therapies, c) Drug discovery technologies, and d) Drug delivery technologies. External experts from biotechs and industry present their commercial drug discovery and development projects in Meet the Expert lectures.\r\nLectures will be completed with Journal Clubs on different topics of drug development. Students also prepare podcasts on interesting topics, like hot topics in science, historical cases, challenges in drug discovery and development, ethical considerations, business-related topics etc.","valueSv":"This course consists of topics divided into the following areas: a) General aspects of drug discovery and development processes, b) Biologicals and advanced therapies, c) Drug discovery technologies, and d) Drug delivery technologies. External experts from biotechs and industry present their commercial drug discovery and development projects in Meet the Expert lectures.\r\nLectures will be completed with Journal Clubs on different topics of drug development. Students also prepare podcasts on interesting topics, like hot topics in science, historical cases, challenges in drug discovery and development, ethical considerations, business-related topics etc."}},{"title":{"valueFi":"Suoritustavat","valueEn":"Study methods","valueSv":""},"content":{"valueFi":"Major subject students (8 ECTS): \r\nParticipation on lectures given by internal and external experts. Kick-off lecture (1st lecture) and Meet the Expert lectures are mandatory.\r\nJournal Club presentation prepared in groups of 3-4 students, active participation to the discussions in the Journal Clubs moderated by a staff member. Mandatory presence in the Journal Clubs. \r\nPodcast presentations prepared in groups of 1-3 students.\r\nLearning journals on Meet the Expert lectures and podcasts prepared by other groups.  \r\nFinal written examination.\r\n\r\nMinor subject students (5 ECTS): \r\nParticipation on lectures given by internal and external experts. Kick-off lecture (1st lecture) is mandatory.\r\nJournal Club presentation prepared in groups of 3-4 students, active participation to the discussions in the Journal Clubs moderated by a staff member. Mandatory presence in the Journal Clubs. \r\nFinal written examination.","valueEn":"Major subject students (8 ECTS): \r\nParticipation on lectures given by internal and external experts. Kick-off lecture (1st lecture) and Meet the Expert lectures are mandatory.\r\nJournal Club presentation prepared in groups of 3-4 students, active participation to the discussions in the Journal Clubs moderated by a staff member. Mandatory presence in the Journal Clubs. \r\nPodcast presentations prepared in groups of 1-3 students.\r\nLearning journals on Meet the Expert lectures and podcasts prepared by other groups.  \r\nFinal written examination.\r\n\r\nMinor subject students (5 ECTS): \r\nParticipation on lectures given by internal and external experts. Kick-off lecture (1st lecture) is mandatory.\r\nJournal Club presentation prepared in groups of 3-4 students, active participation to the discussions in the Journal Clubs moderated by a staff member. Mandatory presence in the Journal Clubs. \r\nFinal written examination.","valueSv":""}},{"title":{"valueFi":"Toteutustavat","valueEn":"Course unit methods","valueSv":""},"content":{"valueFi":"Major subject students (8 ECTS): \r\nLectures (46-50 h), Journal Clubs (12-14 h), listening of podcasts (6-8 h), preparation of a podcast and a Journal Club presentation, learning journals (Meet the Expert and podcast), exam (approx. 140 h).\r\n\r\nMinor subject students (5 ECTS):\r\nLectures (46-50 h), Journal Clubs (12-14 h), preparation of a Journal Club presentation, examination (approx. 74 h).","valueEn":"Major subject students (8 ECTS): \r\nLectures (46-50 h), Journal Clubs (12-14 h), listening of podcasts (6-8 h), preparation of a podcast and a Journal Club presentation, learning journals (Meet the Expert and podcast), exam (approx. 140 h).\r\n\r\nMinor subject students (5 ECTS):\r\nLectures (46-50 h), Journal Clubs (12-14 h), preparation of a Journal Club presentation, examination (approx. 74 h).","valueSv":""}},{"title":{"valueFi":"Oppimateriaalit","valueEn":"Learning material","valueSv":""},"content":{"valueFi":"Lecture materials, study materials for Journal Clubs, guidelines regulating drug development, databanks, relevant published reviews and scientific articles.\r\n\r\nRecommended reading: \r\nB.E. Blass, Basic principles of drug discovery and development, Amsterdam, Academic Press, 2021\r\nJ.I. Gallin, F.P. Ognibene and L. Lee Johnson, Principles and practice of clinical research, Academic Press, 2017","valueEn":"Lecture materials, study materials for Journal Clubs, guidelines regulating drug development, databanks, relevant published reviews and scientific articles.\r\n\r\nRecommended reading: \r\nB.E. Blass, Basic principles of drug discovery and development, Amsterdam, Academic Press, 2021\r\nJ.I. Gallin, F.P. Ognibene and L. Lee Johnson, Principles and practice of clinical research, Academic Press, 2017","valueSv":""}},{"title":{"valueFi":"Lisätiedot","valueEn":"Further information","valueSv":""},"content":{"valueFi":"The course is 8 ECTS credits for the students in Drug Discovery and Development track and Pharmacy master students in Åbo Akademi University. The course is 5 ECTS credits for minor subject students in Biomedical Imaging and Molecular Biotechnology and Diagnostics as well as for JOO and exchange students.\r\nMinor students are selected on the basis of their application and previous relevant studies in pharmacology. The quota for minor subject students is 1-5. If there are more applicants than can be admitted to the course, the students are selected based on the application and previous studies relevant for the course. In the case of an even situation the admission is done by lot.\r\nThe course starts every year after the Orientation Days i.e. the last week of August or the first week of September.","valueEn":"The course is 8 ECTS credits for the students in Drug Discovery and Development track and Pharmacy master students in Åbo Akademi University. The course is 5 ECTS credits for minor subject students in Biomedical Imaging and Molecular Biotechnology and Diagnostics as well as for JOO and exchange students.\r\nMinor students are selected on the basis of their application and previous relevant studies in pharmacology. The quota for minor subject students is 1-5. If there are more applicants than can be admitted to the course, the students are selected based on the application and previous studies relevant for the course. In the case of an even situation the admission is done by lot.\r\nThe course starts every year after the Orientation Days i.e. the last week of August or the first week of September.","valueSv":""}},{"title":{"valueFi":"Kurssikirjallisuus","valueEn":"Literature","valueSv":""},"content":{"valueFi":"","valueEn":"","valueSv":""}},{"title":{"valueFi":"Esitietovaatimukset","valueEn":"Qualifications","valueSv":""},"content":{"valueFi":"","valueEn":"","valueSv":""}},{"title":{"valueFi":"Arviointiasteikko","valueEn":"Assessment scale","valueSv":""},"content":{"valueFi":"0-5","valueEn":"0-5","valueSv":"0-5"}},{"title":{"valueFi":"Arviointikriteerit","valueEn":"Assessment criteria","valueSv":""},"content":{"valueFi":"Evaluation criteria are based on knowledge of the entire area of the study module, as measured by a written examination (70 % of the grade) and Journal Club presentation and activity during the Journal Club sessions assessed by the Moderator (30 % of the grade).\r\n\r\nFor 8 ECTS student has to return Learning journals (Meet the Expert and podcast) which are assessed Pass/Fail. The prepared podcast is assessed Pass/Fail.","valueEn":"Evaluation criteria are based on knowledge of the entire area of the study module, as measured by a written examination (70 % of the grade) and Journal Club presentation and activity during the Journal Club sessions assessed by the Moderator (30 % of the grade).\r\n\r\nFor 8 ECTS student has to return Learning journals (Meet the Expert and podcast) which are assessed Pass/Fail. The prepared podcast is assessed Pass/Fail.","valueSv":""}},{"title":{"valueFi":"Arviointikriteerit 2","valueEn":"Assessment criteria 2","valueSv":""},"content":{"valueFi":"","valueEn":"","valueSv":""}},{"title":{"valueFi":"Arviointikriteerit 3","valueEn":"Assessment criteria 3","valueSv":""},"content":{"valueFi":"","valueEn":"","valueSv":""}},{"title":{"valueFi":"Arviointikriteerit 4","valueEn":"Assessment criteria 4","valueSv":""},"content":{"valueFi":"","valueEn":"","valueSv":""}},{"title":{"valueFi":"Kielet","valueEn":"Languages","valueSv":""},"content":{"valueFi":"englanti","valueEn":"English","valueSv":"engelska"}},{"title":{"valueFi":"Taso","valueEn":"Level","valueSv":""},"content":{"valueFi":"Syventävät opinnot","valueEn":"Advanced Studies","valueSv":""}},{"title":{"valueFi":"Oppiaine","valueEn":"Subject","valueSv":""},"content":{"valueFi":"Drug Discovery and Development","valueEn":"Drug Discovery and Development","valueSv":"Drug Discovery and Development"}},{"title":{"valueFi":"Vastuuhenkilöt","valueEn":"Person in charge","valueSv":""},"content":{"valueFi":"Virpi Talman","valueEn":"Virpi Talman","valueSv":"Virpi Talman"}},{"title":{"valueFi":"Luokittelu","valueEn":"Classification","valueSv":""},"content":{"valueFi":"","valueEn":"","valueSv":""}},{"title":{"valueFi":"Linkit","valueEn":"Links","valueSv":""},"content":{"valueFi":"","valueEn":"","valueSv":""}}]}